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Aleck's avatar

Thanks!

Coincidentally, I am preparing an EU proposal on microplastics effects to the human brain.

We will be using organoids, spheroids, microfluidics, and brain-on-a-chip models + some limited

animal models. We have an "organoid ethics" specialist on board because, this is an actual issue. You have human stem cell derived organoids which are alive and can actually generate electrical pulses and then you zap them with drugs or pollutants. Ethical? Also, we were going to have zebrafish as an animal model because they are so simple that they bypass certain restrictions from animal testing and so often used instead of mouse models.

BTW spheroids also can generate networks of neurons (outside the spheroid) that are active.

Back to writing....

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Houston Wood's avatar

I look forward to my Monday nights here in Hawaii to see what gems you've come up with that week. Again you educated me and made me think about new stuff. Thanks.

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